The OAS Secretary General expressed regret at Venezuela's decision to "denounce this legal instrument, one of the pillars of the legal regulations that protect the defense of human rights in the hemisphere," but he also "expressed his hope that in the year that must elapse before the decision becomes effective, as established by Art.78, the government of the Bolivarian Republic of Venezuela may reconsider its decision."

In March 2012, in Case 11.706, Yanomami Indigenous People of Haximú v. Venezuela (Friendly Settlement 32/12), Venezuela "made a commitment to promote the establishment of a plan for permanent and joint supervision and control, in order to monitor and control the access of garimpeiros and illegal mining in the Yanomami area."